Does RASBURICASE Cause Thymus hypoplasia? 70 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 70 reports of Thymus hypoplasia have been filed in association with RASBURICASE (Elitek). This represents 7.9% of all adverse event reports for RASBURICASE.
70
Reports of Thymus hypoplasia with RASBURICASE
7.9%
of all RASBURICASE reports
6
Deaths
70
Hospitalizations
How Dangerous Is Thymus hypoplasia From RASBURICASE?
Of the 70 reports, 6 (8.6%) resulted in death, 70 (100.0%) required hospitalization.
Is Thymus hypoplasia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for RASBURICASE. However, 70 reports have been filed with the FAERS database.
What Other Side Effects Does RASBURICASE Cause?
Tumour lysis syndrome (116)
Methaemoglobinaemia (92)
Off label use (90)
Product use in unapproved indication (76)
Bacterial infection (75)
Fungal infection (73)
Cellulitis (72)
Clostridium difficile colitis (72)
Lymphoid tissue hypoplasia (72)
Lymphopenia (72)
What Other Drugs Cause Thymus hypoplasia?
CYCLOPHOSPHAMIDE (148)
CYTARABINE (148)
DAUNORUBICIN (148)
DEXAMETHASONE (148)
ETOPOSIDE (148)
FILGRASTIM (144)
CYCLOSPORINE (111)
MERCAPTOPURINE (84)
METHOTREXATE (84)
METHYLPREDNISOLONE (84)
Which RASBURICASE Alternatives Have Lower Thymus hypoplasia Risk?
RASBURICASE vs RAVULIZUMAB
RASBURICASE vs RAVULIZUMAB-CWVZ
RASBURICASE vs REBAMIPIDE
RASBURICASE vs REBETOL
RASBURICASE vs REBIF