Does RASBURICASE Cause Pyrexia? 21 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 21 reports of Pyrexia have been filed in association with RASBURICASE (Elitek). This represents 2.4% of all adverse event reports for RASBURICASE.
21
Reports of Pyrexia with RASBURICASE
2.4%
of all RASBURICASE reports
4
Deaths
14
Hospitalizations
How Dangerous Is Pyrexia From RASBURICASE?
Of the 21 reports, 4 (19.0%) resulted in death, 14 (66.7%) required hospitalization, and 5 (23.8%) were considered life-threatening.
Is Pyrexia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for RASBURICASE. However, 21 reports have been filed with the FAERS database.
What Other Side Effects Does RASBURICASE Cause?
Tumour lysis syndrome (116)
Methaemoglobinaemia (92)
Off label use (90)
Product use in unapproved indication (76)
Bacterial infection (75)
Fungal infection (73)
Cellulitis (72)
Clostridium difficile colitis (72)
Lymphoid tissue hypoplasia (72)
Lymphopenia (72)
What Other Drugs Cause Pyrexia?
ADALIMUMAB (12,160)
METHOTREXATE (10,158)
RITUXIMAB (10,061)
PREDNISONE (8,141)
ETANERCEPT (7,626)
INFLIXIMAB (6,560)
ACETAMINOPHEN (6,414)
CYCLOPHOSPHAMIDE (6,126)
TOCILIZUMAB (5,529)
LENALIDOMIDE (5,496)
Which RASBURICASE Alternatives Have Lower Pyrexia Risk?
RASBURICASE vs RAVULIZUMAB
RASBURICASE vs RAVULIZUMAB-CWVZ
RASBURICASE vs REBAMIPIDE
RASBURICASE vs REBETOL
RASBURICASE vs REBIF