Does REGORAFENIB Cause Hepatic failure? 115 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 115 reports of Hepatic failure have been filed in association with REGORAFENIB (Stivarga). This represents 1.2% of all adverse event reports for REGORAFENIB.
115
Reports of Hepatic failure with REGORAFENIB
1.2%
of all REGORAFENIB reports
78
Deaths
57
Hospitalizations
How Dangerous Is Hepatic failure From REGORAFENIB?
Of the 115 reports, 78 (67.8%) resulted in death, 57 (49.6%) required hospitalization, and 16 (13.9%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for REGORAFENIB. However, 115 reports have been filed with the FAERS database.
What Other Side Effects Does REGORAFENIB Cause?
Off label use (1,906)
Fatigue (1,530)
Palmar-plantar erythrodysaesthesia syndrome (1,230)
Diarrhoea (1,221)
Decreased appetite (941)
Asthenia (825)
Death (813)
Dysphonia (702)
Nausea (688)
Pain in extremity (686)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which REGORAFENIB Alternatives Have Lower Hepatic failure Risk?
REGORAFENIB vs REGORAFENIB\REGORAFENIB
REGORAFENIB vs RELATLIMAB
REGORAFENIB vs RELPAX
REGORAFENIB vs RELUGOLIX
REGORAFENIB vs REMDESIVIR