Does RIBOCICLIB Cause Hepatic necrosis? 27 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 27 reports of Hepatic necrosis have been filed in association with RIBOCICLIB (KISQALI). This represents 0.1% of all adverse event reports for RIBOCICLIB.
27
Reports of Hepatic necrosis with RIBOCICLIB
0.1%
of all RIBOCICLIB reports
10
Deaths
14
Hospitalizations
How Dangerous Is Hepatic necrosis From RIBOCICLIB?
Of the 27 reports, 10 (37.0%) resulted in death, 14 (51.9%) required hospitalization, and 3 (11.1%) were considered life-threatening.
Is Hepatic necrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for RIBOCICLIB. However, 27 reports have been filed with the FAERS database.
What Other Side Effects Does RIBOCICLIB Cause?
Neutropenia (3,585)
Nausea (3,404)
Fatigue (3,327)
Malignant neoplasm progression (2,468)
Death (2,452)
Vomiting (1,953)
Diarrhoea (1,830)
White blood cell count decreased (1,683)
Pain (1,637)
Metastases to bone (1,538)
What Other Drugs Cause Hepatic necrosis?
ACETAMINOPHEN (216)
CYCLOPHOSPHAMIDE (83)
PREDNISONE (78)
VENLAFAXINE (69)
TACROLIMUS (67)
MYCOPHENOLATE MOFETIL (61)
METHOTREXATE (55)
METHYLPREDNISOLONE (55)
SOMATROPIN (50)
DIMETHYL SULFONE (49)
Which RIBOCICLIB Alternatives Have Lower Hepatic necrosis Risk?
RIBOCICLIB vs RIBOFLAVIN
RIBOCICLIB vs RIBOFLAVIN 5'-PHOSPHATE
RIBOCICLIB vs RIBOFLAVIN 5^-PHOSPHATE
RIBOCICLIB vs RIFABUTIN
RIBOCICLIB vs RIFAMPICIN