Does RUXOLITINIB Cause Hepatic failure? 103 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 103 reports of Hepatic failure have been filed in association with RUXOLITINIB (OPZELURA). This represents 0.2% of all adverse event reports for RUXOLITINIB.
103
Reports of Hepatic failure with RUXOLITINIB
0.2%
of all RUXOLITINIB reports
66
Deaths
58
Hospitalizations
How Dangerous Is Hepatic failure From RUXOLITINIB?
Of the 103 reports, 66 (64.1%) resulted in death, 58 (56.3%) required hospitalization, and 14 (13.6%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for RUXOLITINIB. However, 103 reports have been filed with the FAERS database.
What Other Side Effects Does RUXOLITINIB Cause?
Off label use (12,492)
Death (6,561)
Fatigue (5,663)
Anaemia (3,593)
Haemoglobin decreased (3,297)
Platelet count decreased (3,028)
Diarrhoea (2,531)
Asthenia (2,529)
Dizziness (2,398)
Pneumonia (2,343)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which RUXOLITINIB Alternatives Have Lower Hepatic failure Risk?
RUXOLITINIB vs SABRIL
RUXOLITINIB vs SACCHAROMYCES CEREVISIAE
RUXOLITINIB vs SACITUZUMAB GOVITECAN
RUXOLITINIB vs SACITUZUMAB GOVITECAN-HZIY
RUXOLITINIB vs SACROSIDASE