Does SILTUXIMAB Cause Renal impairment? 5 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 5 reports of Renal impairment have been filed in association with SILTUXIMAB (Sylvant). This represents 1.1% of all adverse event reports for SILTUXIMAB.
5
Reports of Renal impairment with SILTUXIMAB
1.1%
of all SILTUXIMAB reports
3
Deaths
5
Hospitalizations
How Dangerous Is Renal impairment From SILTUXIMAB?
Of the 5 reports, 3 (60.0%) resulted in death, 5 (100.0%) required hospitalization, and 1 (20.0%) were considered life-threatening.
Is Renal impairment Listed in the Official Label?
Yes, Renal impairment is listed as a known adverse reaction in the official FDA drug label for SILTUXIMAB.
What Other Side Effects Does SILTUXIMAB Cause?
Off label use (96)
Drug ineffective (72)
Disease progression (32)
Immune effector cell-associated neurotoxicity syndrome (28)
Death (27)
Cytokine release syndrome (26)
Hypertension (24)
Product use in unapproved indication (24)
Drug effective for unapproved indication (23)
Cataract (19)
What Other Drugs Cause Renal impairment?
LENALIDOMIDE (2,161)
EMTRICITABINE\TENOFOVIR DISOPROXIL (2,128)
TACROLIMUS (2,124)
OMEPRAZOLE (2,075)
LANSOPRAZOLE (2,063)
METHOTREXATE (1,852)
ESOMEPRAZOLE (1,811)
PANTOPRAZOLE (1,713)
SACUBITRIL\VALSARTAN (1,610)
CYCLOSPORINE (1,489)
Which SILTUXIMAB Alternatives Have Lower Renal impairment Risk?
SILTUXIMAB vs SILVER SULFADIAZINE
SILTUXIMAB vs SIMEPREVIR
SILTUXIMAB vs SIMPONI
SILTUXIMAB vs SIMVASTATIN
SILTUXIMAB vs SINGULAIR