Does SIMEPREVIR Cause Hepatic failure? 145 Reports in FDA Database

Q: Does SIMEPREVIR cause Hepatic failure?

145 reports of Hepatic failure have been filed with the FDA for SIMEPREVIR, representing 2.4% of all SIMEPREVIR adverse event reports.

Q: How dangerous is Hepatic failure from SIMEPREVIR?

Of 145 reports, 79 (54.5%) resulted in death and 60 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 145 reports of Hepatic failure have been filed in association with SIMEPREVIR. This represents 2.4% of all adverse event reports for SIMEPREVIR.

145

Reports of Hepatic failure with SIMEPREVIR

2.4%

of all SIMEPREVIR reports

Deaths

Hospitalizations

How Dangerous Is Hepatic failure From SIMEPREVIR?

Of the 145 reports, 79 (54.5%) resulted in death, 60 (41.4%) required hospitalization, and 9 (6.2%) were considered life-threatening.

Is Hepatic failure Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for SIMEPREVIR. However, 145 reports have been filed with the FAERS database.

What Other Side Effects Does SIMEPREVIR Cause?

Off label use (1,166) Anaemia (999) Platelet count decreased (833) White blood cell count decreased (581) Hepatitis c (537) Blood bilirubin increased (467) Drug ineffective (440) Pyrexia (429) Rash (388) Haemoglobin decreased (385)

What Other Drugs Cause Hepatic failure?

ACETAMINOPHEN (1,392) RIBAVIRIN (888) CYCLOPHOSPHAMIDE (629) METHOTREXATE (598) BEVACIZUMAB (558) SOFOSBUVIR (525) RITUXIMAB (513) VINCRISTINE (468) DOXORUBICIN (462) PREDNISOLONE (425)

Which SIMEPREVIR Alternatives Have Lower Hepatic failure Risk?

SIMEPREVIR vs SIMPONI SIMEPREVIR vs SIMVASTATIN SIMEPREVIR vs SINGULAIR SIMEPREVIR vs SINTILIMAB SIMEPREVIR vs SIPONIMOD

SIMEPREVIR Full Profile All Hepatic failure Reports All Drugs Causing Hepatic failure SIMEPREVIR Demographics