Does SIMVASTATIN Cause Hepatic necrosis? 29 Reports in FDA Database
Lower Your Cholesterol — The Natural Way
The Oxidized Cholesterol Strategy: a science-backed plan for heart health.
According to the FDA Adverse Event Reporting System (FAERS), 29 reports of Hepatic necrosis have been filed in association with SIMVASTATIN (Simvastatin). This represents 0.1% of all adverse event reports for SIMVASTATIN.
29
Reports of Hepatic necrosis with SIMVASTATIN
0.1%
of all SIMVASTATIN reports
16
Deaths
19
Hospitalizations
How Dangerous Is Hepatic necrosis From SIMVASTATIN?
Of the 29 reports, 16 (55.2%) resulted in death, 19 (65.5%) required hospitalization, and 9 (31.0%) were considered life-threatening.
Is Hepatic necrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SIMVASTATIN. However, 29 reports have been filed with the FAERS database.
What Other Side Effects Does SIMVASTATIN Cause?
Myalgia (3,919)
Fatigue (2,066)
Arthralgia (1,775)
Drug interaction (1,744)
Nausea (1,676)
Rhabdomyolysis (1,616)
Dyspnoea (1,542)
Headache (1,470)
Drug hypersensitivity (1,433)
Muscular weakness (1,356)
What Other Drugs Cause Hepatic necrosis?
ACETAMINOPHEN (216)
CYCLOPHOSPHAMIDE (83)
PREDNISONE (78)
VENLAFAXINE (69)
TACROLIMUS (67)
MYCOPHENOLATE MOFETIL (61)
METHOTREXATE (55)
METHYLPREDNISOLONE (55)
SOMATROPIN (50)
DIMETHYL SULFONE (49)
Which SIMVASTATIN Alternatives Have Lower Hepatic necrosis Risk?
SIMVASTATIN vs SINGULAIR
SIMVASTATIN vs SINTILIMAB
SIMVASTATIN vs SIPONIMOD
SIMVASTATIN vs SIPULEUCEL-T
SIMVASTATIN vs SIROLIMUS