Does SIROLIMUS Cause Encephalopathy? 31 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 31 reports of Encephalopathy have been filed in association with SIROLIMUS (sirolimus). This represents 0.3% of all adverse event reports for SIROLIMUS.
31
Reports of Encephalopathy with SIROLIMUS
0.3%
of all SIROLIMUS reports
22
Deaths
23
Hospitalizations
How Dangerous Is Encephalopathy From SIROLIMUS?
Of the 31 reports, 22 (71.0%) resulted in death, 23 (74.2%) required hospitalization, and 15 (48.4%) were considered life-threatening.
Is Encephalopathy Listed in the Official Label?
Yes, Encephalopathy is listed as a known adverse reaction in the official FDA drug label for SIROLIMUS.
What Other Side Effects Does SIROLIMUS Cause?
Off label use (1,960)
Drug ineffective (1,005)
Product use in unapproved indication (984)
Transplant rejection (698)
Pneumonia (599)
Product use issue (506)
Alopecia (491)
Acne (482)
Transplant dysfunction (468)
Condition aggravated (433)
What Other Drugs Cause Encephalopathy?
BACLOFEN (845)
METHOTREXATE (775)
ACETAMINOPHEN (608)
IFOSFAMIDE (585)
CYCLOPHOSPHAMIDE (552)
TACROLIMUS (523)
PREDNISONE (489)
DEXAMETHASONE (428)
METFORMIN (418)
ETOPOSIDE (404)
Which SIROLIMUS Alternatives Have Lower Encephalopathy Risk?
SIROLIMUS vs SIRUKUMAB
SIROLIMUS vs SITAGLIPTIN
SIROLIMUS vs SOAP
SIROLIMUS vs SODIUM
SIROLIMUS vs SODIUM BICARBONATE