Does SOFOSBUVIR Cause Encephalopathy? 105 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 105 reports of Encephalopathy have been filed in association with SOFOSBUVIR (Epclusa). This represents 0.6% of all adverse event reports for SOFOSBUVIR.
105
Reports of Encephalopathy with SOFOSBUVIR
0.6%
of all SOFOSBUVIR reports
26
Deaths
62
Hospitalizations
How Dangerous Is Encephalopathy From SOFOSBUVIR?
Of the 105 reports, 26 (24.8%) resulted in death, 62 (59.0%) required hospitalization, and 7 (6.7%) were considered life-threatening.
Is Encephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SOFOSBUVIR. However, 105 reports have been filed with the FAERS database.
What Other Side Effects Does SOFOSBUVIR Cause?
Fatigue (2,004)
Drug ineffective (1,833)
Hepatitis c (1,662)
Headache (1,417)
Nausea (1,211)
Off label use (1,184)
Anaemia (1,065)
Insomnia (940)
Hepatocellular carcinoma (877)
Treatment failure (806)
What Other Drugs Cause Encephalopathy?
BACLOFEN (845)
METHOTREXATE (775)
ACETAMINOPHEN (608)
IFOSFAMIDE (585)
CYCLOPHOSPHAMIDE (552)
TACROLIMUS (523)
PREDNISONE (489)
DEXAMETHASONE (428)
METFORMIN (418)
ETOPOSIDE (404)
Which SOFOSBUVIR Alternatives Have Lower Encephalopathy Risk?
SOFOSBUVIR vs SOFOSBUVIR\VELPATASVIR
SOFOSBUVIR vs SOFOSBUVIR\VELPATASVIR\VOXILAPREVIR
SOFOSBUVIR vs SOLIFENACIN
SOFOSBUVIR vs SOLIRIS
SOFOSBUVIR vs SOLOSTAR