Does SOFOSBUVIR Cause Hyperbilirubinaemia? 260 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 260 reports of Hyperbilirubinaemia have been filed in association with SOFOSBUVIR (Epclusa). This represents 1.5% of all adverse event reports for SOFOSBUVIR.
260
Reports of Hyperbilirubinaemia with SOFOSBUVIR
1.5%
of all SOFOSBUVIR reports
47
Deaths
91
Hospitalizations
How Dangerous Is Hyperbilirubinaemia From SOFOSBUVIR?
Of the 260 reports, 47 (18.1%) resulted in death, 91 (35.0%) required hospitalization, and 4 (1.5%) were considered life-threatening.
Is Hyperbilirubinaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SOFOSBUVIR. However, 260 reports have been filed with the FAERS database.
What Other Side Effects Does SOFOSBUVIR Cause?
Fatigue (2,004)
Drug ineffective (1,833)
Hepatitis c (1,662)
Headache (1,417)
Nausea (1,211)
Off label use (1,184)
Anaemia (1,065)
Insomnia (940)
Hepatocellular carcinoma (877)
Treatment failure (806)
What Other Drugs Cause Hyperbilirubinaemia?
METHOTREXATE (603)
RIBAVIRIN (560)
VINCRISTINE (479)
CYTARABINE (397)
PEGASPARGASE (349)
ACETAMINOPHEN (330)
CYCLOPHOSPHAMIDE (330)
DEXAMETHASONE (315)
CAPECITABINE (279)
PREDNISONE (259)
Which SOFOSBUVIR Alternatives Have Lower Hyperbilirubinaemia Risk?
SOFOSBUVIR vs SOFOSBUVIR\VELPATASVIR
SOFOSBUVIR vs SOFOSBUVIR\VELPATASVIR\VOXILAPREVIR
SOFOSBUVIR vs SOLIFENACIN
SOFOSBUVIR vs SOLIRIS
SOFOSBUVIR vs SOLOSTAR