Hyperbilirubinaemia: Which Medications Cause It? (7,325 Reports Across 552 Drugs)
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Hyperbilirubinaemia has been reported as an adverse event with 552 different drugs in the FDA's FAERS database, with 7,325 total reports. 998 of these reports resulted in death.The drugs most commonly associated with Hyperbilirubinaemia are METHOTREXATE, RIBAVIRIN, and VINCRISTINE.
7,325
Total Reports
552
Drugs Involved
998
Deaths
3,548
Hospitalizations
52.6 yrs
Average Patient Age
43.2% / 56.8%
Female / Male
Which Drugs Cause Hyperbilirubinaemia Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| METHOTREXATE | 603 | 0.2% | 75 | 293 | 43 |
| RIBAVIRIN | 560 | 1.3% | 46 | 183 | 16 |
| VINCRISTINE | 479 | 0.7% | 56 | 226 | 25 |
| CYTARABINE | 397 | 0.9% | 62 | 184 | 34 |
| PEGASPARGASE | 349 | 3.0% | 33 | 145 | 19 |
| ACETAMINOPHEN | 330 | 0.2% | 30 | 237 | 77 |
| CYCLOPHOSPHAMIDE | 330 | 0.3% | 82 | 172 | 28 |
| DEXAMETHASONE | 315 | 0.3% | 46 | 144 | 26 |
| CAPECITABINE | 279 | 0.4% | 18 | 77 | 10 |
| SOFOSBUVIR | 260 | 1.5% | 47 | 91 | 4 |
| PREDNISONE | 259 | 0.2% | 33 | 96 | 16 |
| SIMEPREVIR | 237 | 3.9% | 34 | 57 | 7 |
| BEVACIZUMAB | 211 | 0.3% | 38 | 58 | 23 |
| FLUOROURACIL | 211 | 0.4% | 24 | 60 | 14 |
| DOXORUBICIN | 209 | 0.3% | 52 | 79 | 17 |
| OXALIPLATIN | 207 | 0.4% | 25 | 65 | 17 |
| DASABUVIR | 206 | 5.1% | 23 | 99 | 9 |
| OMBITASVIR\PARITAPREVIR\RITONAVIR | 201 | 4.4% | 21 | 104 | 8 |
| TRASTUZUMAB | 201 | 0.4% | 9 | 67 | 7 |
| DAUNORUBICIN | 199 | 2.0% | 27 | 102 | 11 |