Does FLUOROURACIL Cause Hyperbilirubinaemia? 211 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 211 reports of Hyperbilirubinaemia have been filed in association with FLUOROURACIL (FLUOROURACIL). This represents 0.4% of all adverse event reports for FLUOROURACIL.
211
Reports of Hyperbilirubinaemia with FLUOROURACIL
0.4%
of all FLUOROURACIL reports
24
Deaths
60
Hospitalizations
How Dangerous Is Hyperbilirubinaemia From FLUOROURACIL?
Of the 211 reports, 24 (11.4%) resulted in death, 60 (28.4%) required hospitalization, and 14 (6.6%) were considered life-threatening.
Is Hyperbilirubinaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FLUOROURACIL. However, 211 reports have been filed with the FAERS database.
What Other Side Effects Does FLUOROURACIL Cause?
Diarrhoea (5,373)
Neutropenia (4,400)
Nausea (3,757)
Vomiting (2,836)
Off label use (2,788)
Neuropathy peripheral (2,605)
Thrombocytopenia (2,426)
Fatigue (2,421)
Disease progression (2,377)
Febrile neutropenia (2,230)
What Other Drugs Cause Hyperbilirubinaemia?
METHOTREXATE (603)
RIBAVIRIN (560)
VINCRISTINE (479)
CYTARABINE (397)
PEGASPARGASE (349)
ACETAMINOPHEN (330)
CYCLOPHOSPHAMIDE (330)
DEXAMETHASONE (315)
CAPECITABINE (279)
SOFOSBUVIR (260)
Which FLUOROURACIL Alternatives Have Lower Hyperbilirubinaemia Risk?
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOROURACIL\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOXETINE
FLUOROURACIL vs FLUOXETINE\FLUOXETINE