Does SIMEPREVIR Cause Hyperbilirubinaemia? 237 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 237 reports of Hyperbilirubinaemia have been filed in association with SIMEPREVIR. This represents 3.9% of all adverse event reports for SIMEPREVIR.
237
Reports of Hyperbilirubinaemia with SIMEPREVIR
3.9%
of all SIMEPREVIR reports
34
Deaths
57
Hospitalizations
How Dangerous Is Hyperbilirubinaemia From SIMEPREVIR?
Of the 237 reports, 34 (14.3%) resulted in death, 57 (24.1%) required hospitalization, and 7 (3.0%) were considered life-threatening.
Is Hyperbilirubinaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SIMEPREVIR. However, 237 reports have been filed with the FAERS database.
What Other Side Effects Does SIMEPREVIR Cause?
Off label use (1,166)
Anaemia (999)
Platelet count decreased (833)
White blood cell count decreased (581)
Hepatitis c (537)
Blood bilirubin increased (467)
Drug ineffective (440)
Pyrexia (429)
Rash (388)
Haemoglobin decreased (385)
What Other Drugs Cause Hyperbilirubinaemia?
METHOTREXATE (603)
RIBAVIRIN (560)
VINCRISTINE (479)
CYTARABINE (397)
PEGASPARGASE (349)
ACETAMINOPHEN (330)
CYCLOPHOSPHAMIDE (330)
DEXAMETHASONE (315)
CAPECITABINE (279)
SOFOSBUVIR (260)
Which SIMEPREVIR Alternatives Have Lower Hyperbilirubinaemia Risk?
SIMEPREVIR vs SIMPONI
SIMEPREVIR vs SIMVASTATIN
SIMEPREVIR vs SINGULAIR
SIMEPREVIR vs SINTILIMAB
SIMEPREVIR vs SIPONIMOD