Does TRASTUZUMAB Cause Hyperbilirubinaemia? 201 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 201 reports of Hyperbilirubinaemia have been filed in association with TRASTUZUMAB (Trazimera). This represents 0.4% of all adverse event reports for TRASTUZUMAB.
201
Reports of Hyperbilirubinaemia with TRASTUZUMAB
0.4%
of all TRASTUZUMAB reports
9
Deaths
67
Hospitalizations
How Dangerous Is Hyperbilirubinaemia From TRASTUZUMAB?
Of the 201 reports, 9 (4.5%) resulted in death, 67 (33.3%) required hospitalization, and 7 (3.5%) were considered life-threatening.
Is Hyperbilirubinaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TRASTUZUMAB. However, 201 reports have been filed with the FAERS database.
What Other Side Effects Does TRASTUZUMAB Cause?
Diarrhoea (4,996)
Off label use (3,802)
Nausea (3,499)
Fatigue (3,417)
Myelosuppression (2,552)
Disease progression (2,449)
Death (2,378)
Vomiting (2,244)
Dyspnoea (2,010)
Pyrexia (1,886)
What Other Drugs Cause Hyperbilirubinaemia?
METHOTREXATE (603)
RIBAVIRIN (560)
VINCRISTINE (479)
CYTARABINE (397)
PEGASPARGASE (349)
ACETAMINOPHEN (330)
CYCLOPHOSPHAMIDE (330)
DEXAMETHASONE (315)
CAPECITABINE (279)
SOFOSBUVIR (260)
Which TRASTUZUMAB Alternatives Have Lower Hyperbilirubinaemia Risk?
TRASTUZUMAB vs TRASTUZUMAB-ANNS
TRASTUZUMAB vs TRASTUZUMAB DERUXTECAN
TRASTUZUMAB vs TRASTUZUMAB-DKST
TRASTUZUMAB vs TRASTUZUMAB-DTTB
TRASTUZUMAB vs TRASTUZUMAB EMTANSINE