Does SORAFENIB Cause Hepatic failure? 250 Reports in FDA Database

Q: Does SORAFENIB cause Hepatic failure?

250 reports of Hepatic failure have been filed with the FDA for SORAFENIB, representing 2.3% of all SORAFENIB adverse event reports.

Q: How dangerous is Hepatic failure from SORAFENIB?

Of 250 reports, 188 (75.2%) resulted in death and 100 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 250 reports of Hepatic failure have been filed in association with SORAFENIB (sorafenib). This represents 2.3% of all adverse event reports for SORAFENIB.

250

Reports of Hepatic failure with SORAFENIB

2.3%

of all SORAFENIB reports

188

Deaths

100

Hospitalizations

How Dangerous Is Hepatic failure From SORAFENIB?

Of the 250 reports, 188 (75.2%) resulted in death, 100 (40.0%) required hospitalization, and 11 (4.4%) were considered life-threatening.

Is Hepatic failure Listed in the Official Label?

Yes, Hepatic failure is listed as a known adverse reaction in the official FDA drug label for SORAFENIB.

What Other Side Effects Does SORAFENIB Cause?

Hepatocellular carcinoma (1,665) Diarrhoea (1,611) Off label use (1,587) Fatigue (1,041) Palmar-plantar erythrodysaesthesia syndrome (1,040) Decreased appetite (906) Death (904) Asthenia (777) Nausea (716) Rash (613)

What Other Drugs Cause Hepatic failure?

ACETAMINOPHEN (1,392) RIBAVIRIN (888) CYCLOPHOSPHAMIDE (629) METHOTREXATE (598) BEVACIZUMAB (558) SOFOSBUVIR (525) RITUXIMAB (513) VINCRISTINE (468) DOXORUBICIN (462) PREDNISOLONE (425)

Which SORAFENIB Alternatives Have Lower Hepatic failure Risk?

SORAFENIB vs SORGHUM HALEPENSE POLLEN SORAFENIB vs SOTAGLIFLOZIN SORAFENIB vs SOTALOL SORAFENIB vs SOTATERCEPT SORAFENIB vs SOTATERCEPT-CSRK

SORAFENIB Full Profile All Hepatic failure Reports All Drugs Causing Hepatic failure SORAFENIB Demographics