Does SORAFENIB Cause Hyperkeratosis? 150 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 150 reports of Hyperkeratosis have been filed in association with SORAFENIB (sorafenib). This represents 1.4% of all adverse event reports for SORAFENIB.
150
Reports of Hyperkeratosis with SORAFENIB
1.4%
of all SORAFENIB reports
12
Deaths
48
Hospitalizations
How Dangerous Is Hyperkeratosis From SORAFENIB?
Of the 150 reports, 12 (8.0%) resulted in death, 48 (32.0%) required hospitalization, and 3 (2.0%) were considered life-threatening.
Is Hyperkeratosis Listed in the Official Label?
Yes, Hyperkeratosis is listed as a known adverse reaction in the official FDA drug label for SORAFENIB.
What Other Side Effects Does SORAFENIB Cause?
Hepatocellular carcinoma (1,665)
Diarrhoea (1,611)
Off label use (1,587)
Fatigue (1,041)
Palmar-plantar erythrodysaesthesia syndrome (1,040)
Decreased appetite (906)
Death (904)
Asthenia (777)
Nausea (716)
Rash (613)
What Other Drugs Cause Hyperkeratosis?
CABOZANTINIB S-MALATE (411)
ADALIMUMAB (332)
SUNITINIB MALATE (170)
ETANERCEPT (168)
METHOTREXATE (149)
VEMURAFENIB (145)
REGORAFENIB (136)
RIPRETINIB (124)
RITUXIMAB (121)
TOCILIZUMAB (103)
Which SORAFENIB Alternatives Have Lower Hyperkeratosis Risk?
SORAFENIB vs SORGHUM HALEPENSE POLLEN
SORAFENIB vs SOTAGLIFLOZIN
SORAFENIB vs SOTALOL
SORAFENIB vs SOTATERCEPT
SORAFENIB vs SOTATERCEPT-CSRK