Does METHOTREXATE Cause Hyperkeratosis? 149 Reports in FDA Database
Grow Your Own Natural Pharmacy at Home
Medicinal Garden Kit — 10 healing herbs, 4,818 seeds + step-by-step guide.
According to the FDA Adverse Event Reporting System (FAERS), 149 reports of Hyperkeratosis have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
149
Reports of Hyperkeratosis with METHOTREXATE
0.1%
of all METHOTREXATE reports
1
Deaths
52
Hospitalizations
How Dangerous Is Hyperkeratosis From METHOTREXATE?
Of the 149 reports, 1 (0.7%) resulted in death, 52 (34.9%) required hospitalization, and 1 (0.7%) were considered life-threatening.
Is Hyperkeratosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 149 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Hyperkeratosis?
CABOZANTINIB S-MALATE (411)
ADALIMUMAB (332)
SUNITINIB MALATE (170)
ETANERCEPT (168)
SORAFENIB (150)
VEMURAFENIB (145)
REGORAFENIB (136)
RIPRETINIB (124)
RITUXIMAB (121)
TOCILIZUMAB (103)
Which METHOTREXATE Alternatives Have Lower Hyperkeratosis Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA