Does VEMURAFENIB Cause Hyperkeratosis? 145 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 145 reports of Hyperkeratosis have been filed in association with VEMURAFENIB (ZELBORAF). This represents 1.7% of all adverse event reports for VEMURAFENIB.
145
Reports of Hyperkeratosis with VEMURAFENIB
1.7%
of all VEMURAFENIB reports
11
Deaths
18
Hospitalizations
How Dangerous Is Hyperkeratosis From VEMURAFENIB?
Of the 145 reports, 11 (7.6%) resulted in death, 18 (12.4%) required hospitalization, and 7 (4.8%) were considered life-threatening.
Is Hyperkeratosis Listed in the Official Label?
Yes, Hyperkeratosis is listed as a known adverse reaction in the official FDA drug label for VEMURAFENIB.
What Other Side Effects Does VEMURAFENIB Cause?
Rash (1,202)
Arthralgia (783)
Off label use (782)
Fatigue (773)
Diarrhoea (655)
Nausea (601)
Pyrexia (569)
Death (505)
Alopecia (445)
Decreased appetite (383)
What Other Drugs Cause Hyperkeratosis?
CABOZANTINIB S-MALATE (411)
ADALIMUMAB (332)
SUNITINIB MALATE (170)
ETANERCEPT (168)
SORAFENIB (150)
METHOTREXATE (149)
REGORAFENIB (136)
RIPRETINIB (124)
RITUXIMAB (121)
TOCILIZUMAB (103)
Which VEMURAFENIB Alternatives Have Lower Hyperkeratosis Risk?
VEMURAFENIB vs VENETOCLAX
VEMURAFENIB vs VENLAFAXINE
VEMURAFENIB vs VENTAVIS
VEMURAFENIB vs VENTOLIN
VEMURAFENIB vs VENTOLIN HFA