Does SORAFENIB Cause Osteonecrosis? 17 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 17 reports of Osteonecrosis have been filed in association with SORAFENIB (sorafenib). This represents 0.2% of all adverse event reports for SORAFENIB.
17
Reports of Osteonecrosis with SORAFENIB
0.2%
of all SORAFENIB reports
1
Deaths
4
Hospitalizations
How Dangerous Is Osteonecrosis From SORAFENIB?
Of the 17 reports, 1 (5.9%) resulted in death, 4 (23.5%) required hospitalization, and 4 (23.5%) were considered life-threatening.
Is Osteonecrosis Listed in the Official Label?
Yes, Osteonecrosis is listed as a known adverse reaction in the official FDA drug label for SORAFENIB.
What Other Side Effects Does SORAFENIB Cause?
Hepatocellular carcinoma (1,665)
Diarrhoea (1,611)
Off label use (1,587)
Fatigue (1,041)
Palmar-plantar erythrodysaesthesia syndrome (1,040)
Decreased appetite (906)
Death (904)
Asthenia (777)
Nausea (716)
Rash (613)
What Other Drugs Cause Osteonecrosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (8,935)
TENOFOVIR DISOPROXIL (7,182)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,338)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,081)
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (1,492)
PREDNISONE (779)
PREDNISOLONE (711)
DENOSUMAB (567)
METHOTREXATE (563)
DEXAMETHASONE (531)
Which SORAFENIB Alternatives Have Lower Osteonecrosis Risk?
SORAFENIB vs SORGHUM HALEPENSE POLLEN
SORAFENIB vs SOTAGLIFLOZIN
SORAFENIB vs SOTALOL
SORAFENIB vs SOTATERCEPT
SORAFENIB vs SOTATERCEPT-CSRK