Does SOTORASIB Cause Constipation? 26 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 26 reports of Constipation have been filed in association with SOTORASIB (LUMAKRAS). This represents 0.9% of all adverse event reports for SOTORASIB.
26
Reports of Constipation with SOTORASIB
0.9%
of all SOTORASIB reports
4
Deaths
10
Hospitalizations
How Dangerous Is Constipation From SOTORASIB?
Of the 26 reports, 4 (15.4%) resulted in death, 10 (38.5%) required hospitalization.
Is Constipation Listed in the Official Label?
Yes, Constipation is listed as a known adverse reaction in the official FDA drug label for SOTORASIB.
What Other Side Effects Does SOTORASIB Cause?
Non-small cell lung cancer (483)
Death (319)
Disease progression (314)
Diarrhoea (284)
Off label use (193)
Nausea (98)
Non-small cell lung cancer metastatic (93)
Hepatotoxicity (91)
Fatigue (87)
Hepatic function abnormal (80)
What Other Drugs Cause Constipation?
LENALIDOMIDE (9,635)
NIRAPARIB (4,128)
ADALIMUMAB (4,063)
SEMAGLUTIDE (4,036)
TIRZEPATIDE (3,417)
ERENUMAB-AOOE (3,104)
MORPHINE (2,979)
OXYCODONE (2,747)
PALBOCICLIB (2,705)
POMALIDOMIDE (2,374)
Which SOTORASIB Alternatives Have Lower Constipation Risk?
SOTORASIB vs SOTROVIMAB
SOTORASIB vs SOVALDI
SOTORASIB vs SOYBEAN OIL
SOTORASIB vs SPARSENTAN
SOTORASIB vs SPARTALIZUMAB