Does SOTORASIB Cause Hepatitis? 15 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 15 reports of Hepatitis have been filed in association with SOTORASIB (LUMAKRAS). This represents 0.5% of all adverse event reports for SOTORASIB.
15
Reports of Hepatitis with SOTORASIB
0.5%
of all SOTORASIB reports
3
Deaths
1
Hospitalizations
How Dangerous Is Hepatitis From SOTORASIB?
Of the 15 reports, 3 (20.0%) resulted in death, 1 (6.7%) required hospitalization, and 2 (13.3%) were considered life-threatening.
Is Hepatitis Listed in the Official Label?
Yes, Hepatitis is listed as a known adverse reaction in the official FDA drug label for SOTORASIB.
What Other Side Effects Does SOTORASIB Cause?
Non-small cell lung cancer (483)
Death (319)
Disease progression (314)
Diarrhoea (284)
Off label use (193)
Nausea (98)
Non-small cell lung cancer metastatic (93)
Hepatotoxicity (91)
Fatigue (87)
Hepatic function abnormal (80)
What Other Drugs Cause Hepatitis?
METHOTREXATE (1,835)
ACETAMINOPHEN (1,450)
TOCILIZUMAB (1,184)
HYDROXYCHLOROQUINE (1,133)
ADALIMUMAB (1,096)
RITUXIMAB (1,017)
ETANERCEPT (1,013)
LEFLUNOMIDE (997)
PEMBROLIZUMAB (935)
NIVOLUMAB (930)
Which SOTORASIB Alternatives Have Lower Hepatitis Risk?
SOTORASIB vs SOTROVIMAB
SOTORASIB vs SOVALDI
SOTORASIB vs SOYBEAN OIL
SOTORASIB vs SPARSENTAN
SOTORASIB vs SPARTALIZUMAB