Does SPIRONOLACTONE Cause Hepatic failure? 90 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 90 reports of Hepatic failure have been filed in association with SPIRONOLACTONE (spironolactone). This represents 0.4% of all adverse event reports for SPIRONOLACTONE.
90
Reports of Hepatic failure with SPIRONOLACTONE
0.4%
of all SPIRONOLACTONE reports
65
Deaths
49
Hospitalizations
How Dangerous Is Hepatic failure From SPIRONOLACTONE?
Of the 90 reports, 65 (72.2%) resulted in death, 49 (54.4%) required hospitalization, and 14 (15.6%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SPIRONOLACTONE. However, 90 reports have been filed with the FAERS database.
What Other Side Effects Does SPIRONOLACTONE Cause?
Acute kidney injury (3,273)
Hyperkalaemia (2,518)
Hypotension (1,583)
Dyspnoea (1,468)
Drug ineffective (1,379)
Hyponatraemia (1,166)
Dizziness (991)
Fatigue (990)
Fall (947)
Off label use (899)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which SPIRONOLACTONE Alternatives Have Lower Hepatic failure Risk?
SPIRONOLACTONE vs SPRYCEL
SPIRONOLACTONE vs STALEVO
SPIRONOLACTONE vs STANNOUS FLUORIDE
SPIRONOLACTONE vs STANOZOLOL
SPIRONOLACTONE vs STAVUDINE