Does SULFASALAZINE Cause Hepatic failure? 30 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 30 reports of Hepatic failure have been filed in association with SULFASALAZINE (Azulfidine EN-tabs). This represents 0.1% of all adverse event reports for SULFASALAZINE.
30
Reports of Hepatic failure with SULFASALAZINE
0.1%
of all SULFASALAZINE reports
5
Deaths
16
Hospitalizations
How Dangerous Is Hepatic failure From SULFASALAZINE?
Of the 30 reports, 5 (16.7%) resulted in death, 16 (53.3%) required hospitalization, and 2 (6.7%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
Yes, Hepatic failure is listed as a known adverse reaction in the official FDA drug label for SULFASALAZINE.
What Other Side Effects Does SULFASALAZINE Cause?
Drug ineffective (22,365)
Rheumatoid arthritis (15,136)
Drug intolerance (11,530)
Pain (11,309)
Fatigue (9,684)
Joint swelling (9,673)
Rash (8,739)
Contraindicated product administered (8,698)
Arthralgia (8,527)
Abdominal discomfort (8,404)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which SULFASALAZINE Alternatives Have Lower Hepatic failure Risk?
SULFASALAZINE vs SULFATHIAZOLE
SULFASALAZINE vs SULFISOMIDINE
SULFASALAZINE vs SULFUR
SULFASALAZINE vs SULFUR HEXAFLUORIDE
SULFASALAZINE vs SULINDAC