Does TEMOZOLOMIDE Cause Aplasia? 12 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 12 reports of Aplasia have been filed in association with TEMOZOLOMIDE (TEMOZOLOMIDE). This represents 0.1% of all adverse event reports for TEMOZOLOMIDE.
12
Reports of Aplasia with TEMOZOLOMIDE
0.1%
of all TEMOZOLOMIDE reports
5
Deaths
6
Hospitalizations
How Dangerous Is Aplasia From TEMOZOLOMIDE?
Of the 12 reports, 5 (41.7%) resulted in death, 6 (50.0%) required hospitalization, and 1 (8.3%) were considered life-threatening.
Is Aplasia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TEMOZOLOMIDE. However, 12 reports have been filed with the FAERS database.
What Other Side Effects Does TEMOZOLOMIDE Cause?
Disease progression (1,562)
Death (1,403)
Off label use (1,357)
Product use in unapproved indication (1,353)
Thrombocytopenia (1,300)
Drug ineffective (1,131)
Nausea (1,071)
Neutropenia (809)
Malignant neoplasm progression (779)
Fatigue (766)
What Other Drugs Cause Aplasia?
CYTARABINE (229)
ETOPOSIDE (217)
CYCLOPHOSPHAMIDE (213)
METHOTREXATE (199)
VINCRISTINE (167)
DOXORUBICIN (144)
CARBOPLATIN (136)
DEXAMETHASONE (129)
RITUXIMAB (98)
IFOSFAMIDE (88)
Which TEMOZOLOMIDE Alternatives Have Lower Aplasia Risk?
TEMOZOLOMIDE vs TEMSIROLIMUS
TEMOZOLOMIDE vs TENAMFETAMINE
TEMOZOLOMIDE vs TENAPANOR
TEMOZOLOMIDE vs TENECTEPLASE
TEMOZOLOMIDE vs TENELIGLIPTIN