Does THALIDOMIDE Cause Osteonecrosis? 16 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 16 reports of Osteonecrosis have been filed in association with THALIDOMIDE (Thalomid). This represents 0.1% of all adverse event reports for THALIDOMIDE.
16
Reports of Osteonecrosis with THALIDOMIDE
0.1%
of all THALIDOMIDE reports
1
Deaths
4
Hospitalizations
How Dangerous Is Osteonecrosis From THALIDOMIDE?
Of the 16 reports, 1 (6.3%) resulted in death, 4 (25.0%) required hospitalization, and 1 (6.3%) were considered life-threatening.
Is Osteonecrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for THALIDOMIDE. However, 16 reports have been filed with the FAERS database.
What Other Side Effects Does THALIDOMIDE Cause?
Plasma cell myeloma (1,652)
Off label use (1,356)
Death (1,161)
Neuropathy peripheral (1,068)
Drug ineffective (789)
Pneumonia (694)
Fatigue (643)
Constipation (461)
Thrombocytopenia (429)
Neutropenia (420)
What Other Drugs Cause Osteonecrosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (8,935)
TENOFOVIR DISOPROXIL (7,182)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,338)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,081)
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (1,492)
PREDNISONE (779)
PREDNISOLONE (711)
DENOSUMAB (567)
METHOTREXATE (563)
DEXAMETHASONE (531)
Which THALIDOMIDE Alternatives Have Lower Osteonecrosis Risk?
THALIDOMIDE vs THALOMID
THALIDOMIDE vs THEOPHYLLINE
THALIDOMIDE vs THEOPHYLLINE ANHYDROUS
THALIDOMIDE vs THIAMINE
THALIDOMIDE vs THIOCOLCHICOSIDE