Does TISAGENLECLEUCEL Cause Asthenia? 51 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 51 reports of Asthenia have been filed in association with TISAGENLECLEUCEL (KYMRIAH). This represents 1.2% of all adverse event reports for TISAGENLECLEUCEL.
51
Reports of Asthenia with TISAGENLECLEUCEL
1.2%
of all TISAGENLECLEUCEL reports
18
Deaths
30
Hospitalizations
How Dangerous Is Asthenia From TISAGENLECLEUCEL?
Of the 51 reports, 18 (35.3%) resulted in death, 30 (58.8%) required hospitalization, and 16 (31.4%) were considered life-threatening.
Is Asthenia Listed in the Official Label?
Yes, Asthenia is listed as a known adverse reaction in the official FDA drug label for TISAGENLECLEUCEL.
What Other Side Effects Does TISAGENLECLEUCEL Cause?
Cytokine release syndrome (1,660)
Pyrexia (1,030)
Malignant neoplasm progression (582)
Hypotension (425)
Immune effector cell-associated neurotoxicity syndrome (416)
Neurotoxicity (411)
Platelet count decreased (397)
White blood cell count decreased (392)
Hypogammaglobulinaemia (374)
Lymphocyte count decreased (365)
What Other Drugs Cause Asthenia?
ADALIMUMAB (9,797)
LENALIDOMIDE (8,192)
METHOTREXATE (6,269)
ETANERCEPT (5,546)
RITUXIMAB (5,489)
PREDNISONE (4,794)
TOCILIZUMAB (3,898)
INFLIXIMAB (3,729)
LEVOTHYROXINE (3,694)
SACUBITRIL\VALSARTAN (3,667)
Which TISAGENLECLEUCEL Alternatives Have Lower Asthenia Risk?
TISAGENLECLEUCEL vs TISLELIZUMAB
TISAGENLECLEUCEL vs TISOTUMAB VEDOTIN
TISAGENLECLEUCEL vs TISOTUMAB VEDOTIN-TFTV
TISAGENLECLEUCEL vs TITANIUM DIOXIDE\ZINC
TISAGENLECLEUCEL vs TIVICAY