Does TISAGENLECLEUCEL Cause Cardiac failure? 26 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 26 reports of Cardiac failure have been filed in association with TISAGENLECLEUCEL (KYMRIAH). This represents 0.6% of all adverse event reports for TISAGENLECLEUCEL.
26
Reports of Cardiac failure with TISAGENLECLEUCEL
0.6%
of all TISAGENLECLEUCEL reports
21
Deaths
8
Hospitalizations
How Dangerous Is Cardiac failure From TISAGENLECLEUCEL?
Of the 26 reports, 21 (80.8%) resulted in death, 8 (30.8%) required hospitalization, and 16 (61.5%) were considered life-threatening.
Is Cardiac failure Listed in the Official Label?
Yes, Cardiac failure is listed as a known adverse reaction in the official FDA drug label for TISAGENLECLEUCEL.
What Other Side Effects Does TISAGENLECLEUCEL Cause?
Cytokine release syndrome (1,660)
Pyrexia (1,030)
Malignant neoplasm progression (582)
Hypotension (425)
Immune effector cell-associated neurotoxicity syndrome (416)
Neurotoxicity (411)
Platelet count decreased (397)
White blood cell count decreased (392)
Hypogammaglobulinaemia (374)
Lymphocyte count decreased (365)
What Other Drugs Cause Cardiac failure?
SACUBITRIL\VALSARTAN (4,504)
FUROSEMIDE (1,841)
APIXABAN (1,575)
CYCLOPHOSPHAMIDE (1,514)
DOXORUBICIN (1,367)
ADALIMUMAB (1,278)
DEXAMETHASONE (1,271)
TREPROSTINIL (1,168)
BISOPROLOL (1,159)
LENALIDOMIDE (1,115)
Which TISAGENLECLEUCEL Alternatives Have Lower Cardiac failure Risk?
TISAGENLECLEUCEL vs TISLELIZUMAB
TISAGENLECLEUCEL vs TISOTUMAB VEDOTIN
TISAGENLECLEUCEL vs TISOTUMAB VEDOTIN-TFTV
TISAGENLECLEUCEL vs TITANIUM DIOXIDE\ZINC
TISAGENLECLEUCEL vs TIVICAY