Does TISAGENLECLEUCEL Cause Lactic acidosis? 20 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 20 reports of Lactic acidosis have been filed in association with TISAGENLECLEUCEL (KYMRIAH). This represents 0.5% of all adverse event reports for TISAGENLECLEUCEL.
20
Reports of Lactic acidosis with TISAGENLECLEUCEL
0.5%
of all TISAGENLECLEUCEL reports
18
Deaths
14
Hospitalizations
How Dangerous Is Lactic acidosis From TISAGENLECLEUCEL?
Of the 20 reports, 18 (90.0%) resulted in death, 14 (70.0%) required hospitalization, and 6 (30.0%) were considered life-threatening.
Is Lactic acidosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TISAGENLECLEUCEL. However, 20 reports have been filed with the FAERS database.
What Other Side Effects Does TISAGENLECLEUCEL Cause?
Cytokine release syndrome (1,660)
Pyrexia (1,030)
Malignant neoplasm progression (582)
Hypotension (425)
Immune effector cell-associated neurotoxicity syndrome (416)
Neurotoxicity (411)
Platelet count decreased (397)
White blood cell count decreased (392)
Hypogammaglobulinaemia (374)
Lymphocyte count decreased (365)
What Other Drugs Cause Lactic acidosis?
METFORMIN (16,316)
AMLODIPINE (886)
LINEZOLID (824)
FUROSEMIDE (698)
ACETAMINOPHEN (561)
METFORMIN\SITAGLIPTIN (557)
ALBUTEROL (467)
EMPAGLIFLOZIN (434)
RAMIPRIL (430)
BISOPROLOL (425)
Which TISAGENLECLEUCEL Alternatives Have Lower Lactic acidosis Risk?
TISAGENLECLEUCEL vs TISLELIZUMAB
TISAGENLECLEUCEL vs TISOTUMAB VEDOTIN
TISAGENLECLEUCEL vs TISOTUMAB VEDOTIN-TFTV
TISAGENLECLEUCEL vs TITANIUM DIOXIDE\ZINC
TISAGENLECLEUCEL vs TIVICAY