Does TISAGENLECLEUCEL Cause Lymphopenia? 35 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 35 reports of Lymphopenia have been filed in association with TISAGENLECLEUCEL (KYMRIAH). This represents 0.8% of all adverse event reports for TISAGENLECLEUCEL.
35
Reports of Lymphopenia with TISAGENLECLEUCEL
0.8%
of all TISAGENLECLEUCEL reports
15
Deaths
14
Hospitalizations
How Dangerous Is Lymphopenia From TISAGENLECLEUCEL?
Of the 35 reports, 15 (42.9%) resulted in death, 14 (40.0%) required hospitalization, and 2 (5.7%) were considered life-threatening.
Is Lymphopenia Listed in the Official Label?
Yes, Lymphopenia is listed as a known adverse reaction in the official FDA drug label for TISAGENLECLEUCEL.
What Other Side Effects Does TISAGENLECLEUCEL Cause?
Cytokine release syndrome (1,660)
Pyrexia (1,030)
Malignant neoplasm progression (582)
Hypotension (425)
Immune effector cell-associated neurotoxicity syndrome (416)
Neurotoxicity (411)
Platelet count decreased (397)
White blood cell count decreased (392)
Hypogammaglobulinaemia (374)
Lymphocyte count decreased (365)
What Other Drugs Cause Lymphopenia?
FINGOLIMOD (1,515)
CYCLOPHOSPHAMIDE (952)
RITUXIMAB (932)
DEXAMETHASONE (814)
PREDNISONE (788)
DIMETHYL (598)
METHOTREXATE (549)
PREDNISOLONE (465)
TACROLIMUS (456)
MYCOPHENOLATE MOFETIL (453)
Which TISAGENLECLEUCEL Alternatives Have Lower Lymphopenia Risk?
TISAGENLECLEUCEL vs TISLELIZUMAB
TISAGENLECLEUCEL vs TISOTUMAB VEDOTIN
TISAGENLECLEUCEL vs TISOTUMAB VEDOTIN-TFTV
TISAGENLECLEUCEL vs TITANIUM DIOXIDE\ZINC
TISAGENLECLEUCEL vs TIVICAY