Does TOCILIZUMAB Cause Osteonecrosis? 104 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 104 reports of Osteonecrosis have been filed in association with TOCILIZUMAB (Tocilizumab-anoh). This represents 0.1% of all adverse event reports for TOCILIZUMAB.
104
Reports of Osteonecrosis with TOCILIZUMAB
0.1%
of all TOCILIZUMAB reports
1
Deaths
37
Hospitalizations
How Dangerous Is Osteonecrosis From TOCILIZUMAB?
Of the 104 reports, 1 (1.0%) resulted in death, 37 (35.6%) required hospitalization, and 1 (1.0%) were considered life-threatening.
Is Osteonecrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOCILIZUMAB. However, 104 reports have been filed with the FAERS database.
What Other Side Effects Does TOCILIZUMAB Cause?
Drug ineffective (32,342)
Rheumatoid arthritis (20,652)
Pain (18,384)
Off label use (18,256)
Arthralgia (15,536)
Joint swelling (14,831)
Fatigue (13,802)
Rash (12,327)
Drug intolerance (11,952)
Contraindicated product administered (11,547)
What Other Drugs Cause Osteonecrosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (8,935)
TENOFOVIR DISOPROXIL (7,182)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,338)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,081)
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (1,492)
PREDNISONE (779)
PREDNISOLONE (711)
DENOSUMAB (567)
METHOTREXATE (563)
DEXAMETHASONE (531)
Which TOCILIZUMAB Alternatives Have Lower Osteonecrosis Risk?
TOCILIZUMAB vs TOCILIZUMAB-AAZG
TOCILIZUMAB vs TOCOPHEROL
TOCILIZUMAB vs TOFACITINIB
TOCILIZUMAB vs TOFERSEN
TOCILIZUMAB vs TOLNAFTATE