Does TOFACITINIB Cause Skin necrosis? 103 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 103 reports of Skin necrosis have been filed in association with TOFACITINIB (XELJANZ XR). This represents 0.1% of all adverse event reports for TOFACITINIB.
103
Reports of Skin necrosis with TOFACITINIB
0.1%
of all TOFACITINIB reports
0
Deaths
96
Hospitalizations
How Dangerous Is Skin necrosis From TOFACITINIB?
Of the 103 reports, 96 (93.2%) required hospitalization, and 19 (18.4%) were considered life-threatening.
Is Skin necrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOFACITINIB. However, 103 reports have been filed with the FAERS database.
What Other Side Effects Does TOFACITINIB Cause?
Drug ineffective (30,382)
Pain (21,659)
Condition aggravated (16,925)
Arthralgia (15,640)
Fatigue (13,551)
Rheumatoid arthritis (12,277)
Off label use (11,736)
Headache (11,061)
Joint swelling (10,686)
Malaise (9,040)
What Other Drugs Cause Skin necrosis?
METHOTREXATE (620)
ADALIMUMAB (576)
RITUXIMAB (565)
TOCILIZUMAB (530)
ABATACEPT (528)
LEFLUNOMIDE (525)
ETANERCEPT (493)
INFLIXIMAB (491)
HYDROXYCHLOROQUINE (482)
CODEINE (481)
Which TOFACITINIB Alternatives Have Lower Skin necrosis Risk?
TOFACITINIB vs TOFERSEN
TOFACITINIB vs TOLNAFTATE
TOFACITINIB vs TOLODODEKIN ALFA
TOFACITINIB vs TOLTERODINE
TOFACITINIB vs TOLVAPTAN