Does TOPIRAMATE Cause Encephalopathy? 146 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 146 reports of Encephalopathy have been filed in association with TOPIRAMATE (Topiramate). This represents 0.5% of all adverse event reports for TOPIRAMATE.
146
Reports of Encephalopathy with TOPIRAMATE
0.5%
of all TOPIRAMATE reports
1
Deaths
91
Hospitalizations
How Dangerous Is Encephalopathy From TOPIRAMATE?
Of the 146 reports, 1 (0.7%) resulted in death, 91 (62.3%) required hospitalization, and 23 (15.8%) were considered life-threatening.
Is Encephalopathy Listed in the Official Label?
Yes, Encephalopathy is listed as a known adverse reaction in the official FDA drug label for TOPIRAMATE.
What Other Side Effects Does TOPIRAMATE Cause?
Drug ineffective (5,553)
Off label use (4,248)
Product use in unapproved indication (2,173)
Headache (1,997)
Drug intolerance (1,820)
Migraine (1,796)
Nausea (1,691)
Seizure (1,535)
Paraesthesia (1,506)
Dizziness (1,466)
What Other Drugs Cause Encephalopathy?
BACLOFEN (845)
METHOTREXATE (775)
ACETAMINOPHEN (608)
IFOSFAMIDE (585)
CYCLOPHOSPHAMIDE (552)
TACROLIMUS (523)
PREDNISONE (489)
DEXAMETHASONE (428)
METFORMIN (418)
ETOPOSIDE (404)
Which TOPIRAMATE Alternatives Have Lower Encephalopathy Risk?
TOPIRAMATE vs TOPOTECAN
TOPIRAMATE vs TOPOTECAN\TOPOTECAN
TOPIRAMATE vs TOPROL
TOPIRAMATE vs TOREMIFENE
TOPIRAMATE vs TORIPALIMAB