Does TOPIRAMATE Cause Knee arthroplasty? 41 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 41 reports of Knee arthroplasty have been filed in association with TOPIRAMATE (Topiramate). This represents 0.1% of all adverse event reports for TOPIRAMATE.
41
Reports of Knee arthroplasty with TOPIRAMATE
0.1%
of all TOPIRAMATE reports
31
Deaths
34
Hospitalizations
How Dangerous Is Knee arthroplasty From TOPIRAMATE?
Of the 41 reports, 31 (75.6%) resulted in death, 34 (82.9%) required hospitalization, and 31 (75.6%) were considered life-threatening.
Is Knee arthroplasty Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOPIRAMATE. However, 41 reports have been filed with the FAERS database.
What Other Side Effects Does TOPIRAMATE Cause?
Drug ineffective (5,553)
Off label use (4,248)
Product use in unapproved indication (2,173)
Headache (1,997)
Drug intolerance (1,820)
Migraine (1,796)
Nausea (1,691)
Seizure (1,535)
Paraesthesia (1,506)
Dizziness (1,466)
What Other Drugs Cause Knee arthroplasty?
ADALIMUMAB (3,627)
ETANERCEPT (3,541)
METHOTREXATE (2,311)
ABATACEPT (2,028)
TOCILIZUMAB (1,881)
HYDROXYCHLOROQUINE (1,828)
LEFLUNOMIDE (1,771)
INFLIXIMAB (1,751)
TOFACITINIB (1,744)
CERTOLIZUMAB PEGOL (1,731)
Which TOPIRAMATE Alternatives Have Lower Knee arthroplasty Risk?
TOPIRAMATE vs TOPOTECAN
TOPIRAMATE vs TOPOTECAN\TOPOTECAN
TOPIRAMATE vs TOPROL
TOPIRAMATE vs TOREMIFENE
TOPIRAMATE vs TORIPALIMAB