Does TOPOTECAN Cause Cardiac failure? 37 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 37 reports of Cardiac failure have been filed in association with TOPOTECAN (HYCAMTIN). This represents 1.1% of all adverse event reports for TOPOTECAN.
37
Reports of Cardiac failure with TOPOTECAN
1.1%
of all TOPOTECAN reports
7
Deaths
19
Hospitalizations
How Dangerous Is Cardiac failure From TOPOTECAN?
Of the 37 reports, 7 (18.9%) resulted in death, 19 (51.4%) required hospitalization, and 3 (8.1%) were considered life-threatening.
Is Cardiac failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOPOTECAN. However, 37 reports have been filed with the FAERS database.
What Other Side Effects Does TOPOTECAN Cause?
Febrile neutropenia (425)
Off label use (390)
Death (332)
Product use in unapproved indication (323)
Neutropenia (255)
Pyrexia (252)
Anaemia (242)
Malignant neoplasm progression (238)
Drug ineffective (216)
Disease progression (207)
What Other Drugs Cause Cardiac failure?
SACUBITRIL\VALSARTAN (4,504)
FUROSEMIDE (1,841)
APIXABAN (1,575)
CYCLOPHOSPHAMIDE (1,514)
DOXORUBICIN (1,367)
ADALIMUMAB (1,278)
DEXAMETHASONE (1,271)
TREPROSTINIL (1,168)
BISOPROLOL (1,159)
LENALIDOMIDE (1,115)
Which TOPOTECAN Alternatives Have Lower Cardiac failure Risk?
TOPOTECAN vs TOPOTECAN\TOPOTECAN
TOPOTECAN vs TOPROL
TOPOTECAN vs TOREMIFENE
TOPOTECAN vs TORIPALIMAB
TOPOTECAN vs TORSEMIDE