Does TOPOTECAN Cause Sepsis? 85 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 85 reports of Sepsis have been filed in association with TOPOTECAN (HYCAMTIN). This represents 2.4% of all adverse event reports for TOPOTECAN.
85
Reports of Sepsis with TOPOTECAN
2.4%
of all TOPOTECAN reports
24
Deaths
54
Hospitalizations
How Dangerous Is Sepsis From TOPOTECAN?
Of the 85 reports, 24 (28.2%) resulted in death, 54 (63.5%) required hospitalization, and 7 (8.2%) were considered life-threatening.
Is Sepsis Listed in the Official Label?
Yes, Sepsis is listed as a known adverse reaction in the official FDA drug label for TOPOTECAN.
What Other Side Effects Does TOPOTECAN Cause?
Febrile neutropenia (425)
Off label use (390)
Death (332)
Product use in unapproved indication (323)
Neutropenia (255)
Pyrexia (252)
Anaemia (242)
Malignant neoplasm progression (238)
Drug ineffective (216)
Disease progression (207)
What Other Drugs Cause Sepsis?
RITUXIMAB (4,043)
CYCLOPHOSPHAMIDE (4,041)
METHOTREXATE (3,933)
ADALIMUMAB (3,169)
DEXAMETHASONE (3,150)
LENALIDOMIDE (2,956)
VINCRISTINE (2,791)
DOXORUBICIN (2,740)
PREDNISONE (2,634)
PREDNISOLONE (2,281)
Which TOPOTECAN Alternatives Have Lower Sepsis Risk?
TOPOTECAN vs TOPOTECAN\TOPOTECAN
TOPOTECAN vs TOPROL
TOPOTECAN vs TOREMIFENE
TOPOTECAN vs TORIPALIMAB
TOPOTECAN vs TORSEMIDE