TRAMETINIB for K-ras gene mutation: Side Effects & Safety Data

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There are 15 adverse event reports in the FDA FAERS database where TRAMETINIB was used for K-ras gene mutation.

Most Reported Side Effects for TRAMETINIB

Side Effect	Reports	%	Deaths	Hosp.
Pyrexia	1,096	18.8%	113	640
Malignant neoplasm progression	807	13.8%	320	205
Product use in unapproved indication	349	6.0%	33	36
Diarrhoea	325	5.6%	42	183
Nausea	301	5.2%	67	172
Rash	290	5.0%	25	96
Vomiting	289	5.0%	59	187
Fatigue	269	4.6%	39	127
Death	240	4.1%	240	40
Chills	227	3.9%	29	128
Asthenia	193	3.3%	42	92
Drug ineffective	192	3.3%	77	53
Anaemia	184	3.2%	32	124
Off label use	176	3.0%	37	38
Metastatic malignant melanoma	173	3.0%	119	75