Does TRAMETINIB Cause Hepatic failure? 24 Reports in FDA Database

Q: Does TRAMETINIB cause Hepatic failure?

24 reports of Hepatic failure have been filed with the FDA for TRAMETINIB, representing 0.4% of all TRAMETINIB adverse event reports.

Q: How dangerous is Hepatic failure from TRAMETINIB?

Of 24 reports, 9 (37.5%) resulted in death and 15 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 24 reports of Hepatic failure have been filed in association with TRAMETINIB. This represents 0.4% of all adverse event reports for TRAMETINIB.

Reports of Hepatic failure with TRAMETINIB

0.4%

of all TRAMETINIB reports

Deaths

Hospitalizations

How Dangerous Is Hepatic failure From TRAMETINIB?

Of the 24 reports, 9 (37.5%) resulted in death, 15 (62.5%) required hospitalization, and 7 (29.2%) were considered life-threatening.

Is Hepatic failure Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for TRAMETINIB. However, 24 reports have been filed with the FAERS database.

What Other Side Effects Does TRAMETINIB Cause?

Pyrexia (1,096) Malignant neoplasm progression (807) Product use in unapproved indication (349) Diarrhoea (325) Nausea (301) Rash (290) Vomiting (289) Fatigue (269) Death (240) Chills (227)

What Other Drugs Cause Hepatic failure?

ACETAMINOPHEN (1,392) RIBAVIRIN (888) CYCLOPHOSPHAMIDE (629) METHOTREXATE (598) BEVACIZUMAB (558) SOFOSBUVIR (525) RITUXIMAB (513) VINCRISTINE (468) DOXORUBICIN (462) PREDNISOLONE (425)

Which TRAMETINIB Alternatives Have Lower Hepatic failure Risk?

TRAMETINIB vs TRAMETINIB DIMETHYL SULFOXIDE TRAMETINIB vs TRANDOLAPRIL TRAMETINIB vs TRANDOLAPRIL\VERAPAMIL TRAMETINIB vs TRANEXAMIC ACID TRAMETINIB vs TRANYLCYPROMINE

TRAMETINIB Full Profile All Hepatic failure Reports All Drugs Causing Hepatic failure TRAMETINIB Demographics