Does TRAMETINIB Cause Osteonecrosis? 15 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 15 reports of Osteonecrosis have been filed in association with TRAMETINIB. This represents 0.3% of all adverse event reports for TRAMETINIB.
15
Reports of Osteonecrosis with TRAMETINIB
0.3%
of all TRAMETINIB reports
13
Deaths
0
Hospitalizations
How Dangerous Is Osteonecrosis From TRAMETINIB?
Of the 15 reports, 13 (86.7%) resulted in death.
Is Osteonecrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TRAMETINIB. However, 15 reports have been filed with the FAERS database.
What Other Side Effects Does TRAMETINIB Cause?
Pyrexia (1,096)
Malignant neoplasm progression (807)
Product use in unapproved indication (349)
Diarrhoea (325)
Nausea (301)
Rash (290)
Vomiting (289)
Fatigue (269)
Death (240)
Chills (227)
What Other Drugs Cause Osteonecrosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (8,935)
TENOFOVIR DISOPROXIL (7,182)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,338)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,081)
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (1,492)
PREDNISONE (779)
PREDNISOLONE (711)
DENOSUMAB (567)
METHOTREXATE (563)
DEXAMETHASONE (531)
Which TRAMETINIB Alternatives Have Lower Osteonecrosis Risk?
TRAMETINIB vs TRAMETINIB DIMETHYL SULFOXIDE
TRAMETINIB vs TRANDOLAPRIL
TRAMETINIB vs TRANDOLAPRIL\VERAPAMIL
TRAMETINIB vs TRANEXAMIC ACID
TRAMETINIB vs TRANYLCYPROMINE