Does TRASTUZUMAB Cause Hepatic failure? 161 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 161 reports of Hepatic failure have been filed in association with TRASTUZUMAB (Trazimera). This represents 0.4% of all adverse event reports for TRASTUZUMAB.
161
Reports of Hepatic failure with TRASTUZUMAB
0.4%
of all TRASTUZUMAB reports
61
Deaths
75
Hospitalizations
How Dangerous Is Hepatic failure From TRASTUZUMAB?
Of the 161 reports, 61 (37.9%) resulted in death, 75 (46.6%) required hospitalization, and 21 (13.0%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TRASTUZUMAB. However, 161 reports have been filed with the FAERS database.
What Other Side Effects Does TRASTUZUMAB Cause?
Diarrhoea (4,996)
Off label use (3,802)
Nausea (3,499)
Fatigue (3,417)
Myelosuppression (2,552)
Disease progression (2,449)
Death (2,378)
Vomiting (2,244)
Dyspnoea (2,010)
Pyrexia (1,886)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which TRASTUZUMAB Alternatives Have Lower Hepatic failure Risk?
TRASTUZUMAB vs TRASTUZUMAB-ANNS
TRASTUZUMAB vs TRASTUZUMAB DERUXTECAN
TRASTUZUMAB vs TRASTUZUMAB-DKST
TRASTUZUMAB vs TRASTUZUMAB-DTTB
TRASTUZUMAB vs TRASTUZUMAB EMTANSINE