Does TRASTUZUMAB Cause Osteonecrosis? 39 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 39 reports of Osteonecrosis have been filed in association with TRASTUZUMAB (Trazimera). This represents 0.1% of all adverse event reports for TRASTUZUMAB.
39
Reports of Osteonecrosis with TRASTUZUMAB
0.1%
of all TRASTUZUMAB reports
0
Deaths
8
Hospitalizations
How Dangerous Is Osteonecrosis From TRASTUZUMAB?
Of the 39 reports, 8 (20.5%) required hospitalization, and 3 (7.7%) were considered life-threatening.
Is Osteonecrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TRASTUZUMAB. However, 39 reports have been filed with the FAERS database.
What Other Side Effects Does TRASTUZUMAB Cause?
Diarrhoea (4,996)
Off label use (3,802)
Nausea (3,499)
Fatigue (3,417)
Myelosuppression (2,552)
Disease progression (2,449)
Death (2,378)
Vomiting (2,244)
Dyspnoea (2,010)
Pyrexia (1,886)
What Other Drugs Cause Osteonecrosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (8,935)
TENOFOVIR DISOPROXIL (7,182)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,338)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,081)
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (1,492)
PREDNISONE (779)
PREDNISOLONE (711)
DENOSUMAB (567)
METHOTREXATE (563)
DEXAMETHASONE (531)
Which TRASTUZUMAB Alternatives Have Lower Osteonecrosis Risk?
TRASTUZUMAB vs TRASTUZUMAB-ANNS
TRASTUZUMAB vs TRASTUZUMAB DERUXTECAN
TRASTUZUMAB vs TRASTUZUMAB-DKST
TRASTUZUMAB vs TRASTUZUMAB-DTTB
TRASTUZUMAB vs TRASTUZUMAB EMTANSINE