Does TREOSULFAN Cause Hepatic failure? 27 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 27 reports of Hepatic failure have been filed in association with TREOSULFAN (GRAFAPEX). This represents 1.6% of all adverse event reports for TREOSULFAN.
27
Reports of Hepatic failure with TREOSULFAN
1.6%
of all TREOSULFAN reports
17
Deaths
9
Hospitalizations
How Dangerous Is Hepatic failure From TREOSULFAN?
Of the 27 reports, 17 (63.0%) resulted in death, 9 (33.3%) required hospitalization, and 2 (7.4%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TREOSULFAN. However, 27 reports have been filed with the FAERS database.
What Other Side Effects Does TREOSULFAN Cause?
Off label use (418)
Cytomegalovirus infection (211)
Mucosal inflammation (199)
Cytomegalovirus infection reactivation (190)
Adenovirus infection (168)
Product use in unapproved indication (161)
Acute graft versus host disease in skin (145)
Drug ineffective (117)
Graft versus host disease in skin (109)
Human herpesvirus 6 infection (104)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which TREOSULFAN Alternatives Have Lower Hepatic failure Risk?
TREOSULFAN vs TREPROSTINIL
TREOSULFAN vs TREPROSTINIL DIOLAMINE
TREOSULFAN vs TRETINOIN
TREOSULFAN vs TRIAMCINOLONE
TREOSULFAN vs TRIAMCINOLONE ACETONIDE