Does TRIHEXYPHENIDYL Cause Encephalopathy? 30 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 30 reports of Encephalopathy have been filed in association with TRIHEXYPHENIDYL (Trihexyphenidyl Hydrochloride). This represents 1.7% of all adverse event reports for TRIHEXYPHENIDYL.
30
Reports of Encephalopathy with TRIHEXYPHENIDYL
1.7%
of all TRIHEXYPHENIDYL reports
22
Deaths
22
Hospitalizations
How Dangerous Is Encephalopathy From TRIHEXYPHENIDYL?
Of the 30 reports, 22 (73.3%) resulted in death, 22 (73.3%) required hospitalization, and 18 (60.0%) were considered life-threatening.
Is Encephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TRIHEXYPHENIDYL. However, 30 reports have been filed with the FAERS database.
What Other Side Effects Does TRIHEXYPHENIDYL Cause?
Drug ineffective (186)
Off label use (168)
Toxicity to various agents (134)
Somnolence (132)
Coma (123)
Drug abuse (100)
Confusional state (88)
Nausea (76)
Dystonia (68)
Respiratory failure (66)
What Other Drugs Cause Encephalopathy?
BACLOFEN (845)
METHOTREXATE (775)
ACETAMINOPHEN (608)
IFOSFAMIDE (585)
CYCLOPHOSPHAMIDE (552)
TACROLIMUS (523)
PREDNISONE (489)
DEXAMETHASONE (428)
METFORMIN (418)
ETOPOSIDE (404)
Which TRIHEXYPHENIDYL Alternatives Have Lower Encephalopathy Risk?
TRIHEXYPHENIDYL vs TRILACICLIB
TRIHEXYPHENIDYL vs TRILEPTAL
TRIHEXYPHENIDYL vs TRIMEBUTINE
TRIHEXYPHENIDYL vs TRIMEPRAZINE
TRIHEXYPHENIDYL vs TRIMETAZIDINE