Does VALPROIC ACID Cause Encephalopathy? 248 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 248 reports of Encephalopathy have been filed in association with VALPROIC ACID (Valproic Acid). This represents 1.2% of all adverse event reports for VALPROIC ACID.
248
Reports of Encephalopathy with VALPROIC ACID
1.2%
of all VALPROIC ACID reports
19
Deaths
153
Hospitalizations
How Dangerous Is Encephalopathy From VALPROIC ACID?
Of the 248 reports, 19 (7.7%) resulted in death, 153 (61.7%) required hospitalization, and 28 (11.3%) were considered life-threatening.
Is Encephalopathy Listed in the Official Label?
Yes, Encephalopathy is listed as a known adverse reaction in the official FDA drug label for VALPROIC ACID.
What Other Side Effects Does VALPROIC ACID Cause?
Drug ineffective (3,511)
Drug interaction (1,542)
Toxicity to various agents (1,517)
Off label use (1,503)
Seizure (1,335)
Foetal exposure during pregnancy (1,046)
Somnolence (831)
Completed suicide (723)
Overdose (691)
Condition aggravated (673)
What Other Drugs Cause Encephalopathy?
BACLOFEN (845)
METHOTREXATE (775)
ACETAMINOPHEN (608)
IFOSFAMIDE (585)
CYCLOPHOSPHAMIDE (552)
TACROLIMUS (523)
PREDNISONE (489)
DEXAMETHASONE (428)
METFORMIN (418)
ETOPOSIDE (404)
Which VALPROIC ACID Alternatives Have Lower Encephalopathy Risk?
VALPROIC ACID vs VALPROMIDE
VALPROIC ACID vs VALSARTAN
VALPROIC ACID vs VALTREX
VALPROIC ACID vs VAMOROLONE
VALPROIC ACID vs VANCOMYCIN