Does VALPROIC ACID Cause Hepatic failure? 160 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 160 reports of Hepatic failure have been filed in association with VALPROIC ACID (Valproic Acid). This represents 0.8% of all adverse event reports for VALPROIC ACID.
160
Reports of Hepatic failure with VALPROIC ACID
0.8%
of all VALPROIC ACID reports
120
Deaths
41
Hospitalizations
How Dangerous Is Hepatic failure From VALPROIC ACID?
Of the 160 reports, 120 (75.0%) resulted in death, 41 (25.6%) required hospitalization, and 15 (9.4%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
Yes, Hepatic failure is listed as a known adverse reaction in the official FDA drug label for VALPROIC ACID.
What Other Side Effects Does VALPROIC ACID Cause?
Drug ineffective (3,511)
Drug interaction (1,542)
Toxicity to various agents (1,517)
Off label use (1,503)
Seizure (1,335)
Foetal exposure during pregnancy (1,046)
Somnolence (831)
Completed suicide (723)
Overdose (691)
Condition aggravated (673)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which VALPROIC ACID Alternatives Have Lower Hepatic failure Risk?
VALPROIC ACID vs VALPROMIDE
VALPROIC ACID vs VALSARTAN
VALPROIC ACID vs VALTREX
VALPROIC ACID vs VAMOROLONE
VALPROIC ACID vs VANCOMYCIN