Does VINCRISTINE Cause Osteonecrosis? 256 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 256 reports of Osteonecrosis have been filed in association with VINCRISTINE (VinCRIStine Sulfate). This represents 0.4% of all adverse event reports for VINCRISTINE.
256
Reports of Osteonecrosis with VINCRISTINE
0.4%
of all VINCRISTINE reports
10
Deaths
47
Hospitalizations
How Dangerous Is Osteonecrosis From VINCRISTINE?
Of the 256 reports, 10 (3.9%) resulted in death, 47 (18.4%) required hospitalization, and 4 (1.6%) were considered life-threatening.
Is Osteonecrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VINCRISTINE. However, 256 reports have been filed with the FAERS database.
What Other Side Effects Does VINCRISTINE Cause?
Febrile neutropenia (8,676)
Off label use (6,562)
Disease progression (5,252)
Neutropenia (4,982)
Drug ineffective (4,084)
Pyrexia (3,460)
Product use in unapproved indication (3,073)
Thrombocytopenia (2,940)
Sepsis (2,791)
Anaemia (2,603)
What Other Drugs Cause Osteonecrosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (8,935)
TENOFOVIR DISOPROXIL (7,182)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,338)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,081)
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (1,492)
PREDNISONE (779)
PREDNISOLONE (711)
DENOSUMAB (567)
METHOTREXATE (563)
DEXAMETHASONE (531)
Which VINCRISTINE Alternatives Have Lower Osteonecrosis Risk?
VINCRISTINE vs VINDESINE
VINCRISTINE vs VINORELBINE
VINCRISTINE vs VINORELBINE\VINORELBINE
VINCRISTINE vs VIREAD
VINCRISTINE vs VISIPAQUE