Does VOXELOTOR Cause Osteonecrosis? 123 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 123 reports of Osteonecrosis have been filed in association with VOXELOTOR (OXBRYTA). This represents 0.6% of all adverse event reports for VOXELOTOR.
123
Reports of Osteonecrosis with VOXELOTOR
0.6%
of all VOXELOTOR reports
0
Deaths
36
Hospitalizations
How Dangerous Is Osteonecrosis From VOXELOTOR?
Of the 123 reports, 36 (29.3%) required hospitalization, and 2 (1.6%) were considered life-threatening.
Is Osteonecrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VOXELOTOR. However, 123 reports have been filed with the FAERS database.
What Other Side Effects Does VOXELOTOR Cause?
Sickle cell anaemia with crisis (11,023)
Product dose omission issue (5,122)
Diarrhoea (3,173)
Off label use (2,364)
Nausea (2,003)
Headache (1,683)
Abdominal pain upper (1,165)
Pain (1,059)
Therapy cessation (1,038)
Fatigue (1,004)
What Other Drugs Cause Osteonecrosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (8,935)
TENOFOVIR DISOPROXIL (7,182)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,338)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,081)
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (1,492)
PREDNISONE (779)
PREDNISOLONE (711)
DENOSUMAB (567)
METHOTREXATE (563)
DEXAMETHASONE (531)
Which VOXELOTOR Alternatives Have Lower Osteonecrosis Risk?
VOXELOTOR vs VUTRISIRAN
VOXELOTOR vs VX-770
VOXELOTOR vs VX-950
VOXELOTOR vs VYVANSE
VOXELOTOR vs WARFARIN