Antiarrhythmic [EPC]: Side Effects & Safety Data for 13 Drugs
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Antiarrhythmic [EPC] includes 13 drugs with a combined 67,630 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.
13
Drugs in Class
67,630
Combined Reports
All Antiarrhythmic [EPC] Drugs Ranked by Reports
| Drug | Brand Name | Reports | Deaths | Hosp. | Death Rate |
|---|---|---|---|---|---|
| AMIODARONE | Amiodarone Hydrochloride | 25,143 | 3,845 | 13,711 | 15.3% |
| LIDOCAINE | Burn Relief | 22,732 | 1,738 | 5,570 | 7.6% |
| DOFETILIDE | Dofetilide | 5,063 | 428 | 1,446 | 8.5% |
| FLECAINIDE | Flecainide Acetate | 4,388 | 607 | 2,073 | 13.8% |
| SOTALOL | Sotalol | 3,680 | 336 | 1,424 | 9.1% |
| DRONEDARONE | Multaq | 2,735 | 115 | 611 | 4.2% |
| PROPAFENONE | Propafenone Hydrochloride | 1,951 | 221 | 796 | 11.3% |
| MEXILETINE | MEXILETINE HYDROCHLORIDE | 680 | 73 | 316 | 10.7% |
| DISOPYRAMIDE | Disopyramide Phosphate | 619 | 23 | 113 | 3.7% |
| QUINIDINE | Quinidine Gluconate | 324 | 42 | 91 | 13.0% |
| PROCAINAMIDE | Procainamide Hydrochloride | 227 | 19 | 99 | 8.4% |
| LIDOCAINE ANHYDROUS | XYLOCAINE MPF | 62 | 1 | 37 | 1.6% |
| IBUTILIDE | Ibutilide Fumarate | 26 | 2 | 12 | 7.7% |
Common Side Effects in Antiarrhythmic [EPC] Drugs
| Side Effect | Reports | Deaths |
|---|---|---|
| Drug ineffective | 8,396 | 588 |
| Off label use | 4,999 | 715 |
| Dyspnoea | 3,645 | 584 |
| Product adhesion issue | 3,444 | 1 |
| Product quality issue | 3,233 | 4 |
| Toxicity to various agents | 3,124 | 1,054 |
| Atrial fibrillation | 2,818 | 221 |
| Drug interaction | 2,658 | 269 |
| Hypotension | 2,589 | 299 |
| Bradycardia | 2,433 | 199 |