Drug interaction: Which Medications Cause It? (108,246 Reports Across 1,821 Drugs)
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Drug interaction has been reported as an adverse event with 1,821 different drugs in the FDA's FAERS database, with 108,246 total reports. 9,063 of these reports resulted in death.The drugs most commonly associated with Drug interaction are QUETIAPINE, TACROLIMUS, and SERTRALINE.
108,246
Total Reports
1,821
Drugs Involved
9,063
Deaths
49,017
Hospitalizations
57.6 yrs
Average Patient Age
51.4% / 48.6%
Female / Male
Which Drugs Cause Drug interaction Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| QUETIAPINE | 3,577 | 4.9% | 514 | 1,814 | 429 |
| TACROLIMUS | 2,896 | 3.2% | 184 | 1,495 | 238 |
| SERTRALINE | 2,504 | 4.2% | 365 | 1,174 | 244 |
| ATORVASTATIN | 2,358 | 3.0% | 204 | 1,219 | 270 |
| METHOTREXATE | 2,287 | 0.9% | 214 | 1,109 | 256 |
| AMLODIPINE | 2,177 | 3.4% | 124 | 968 | 280 |
| WARFARIN | 2,056 | 5.0% | 179 | 1,114 | 214 |
| FLUOXETINE | 2,054 | 6.6% | 248 | 1,053 | 299 |
| OMEPRAZOLE | 1,882 | 2.2% | 193 | 1,063 | 327 |
| FUROSEMIDE | 1,871 | 3.6% | 172 | 1,321 | 276 |
| VENLAFAXINE | 1,860 | 3.9% | 270 | 859 | 247 |
| CLOPIDOGREL BISULFATE | 1,846 | 4.0% | 198 | 1,100 | 200 |
| ACETAMINOPHEN | 1,805 | 1.3% | 370 | 857 | 340 |
| SIMVASTATIN | 1,744 | 6.4% | 221 | 1,037 | 204 |
| METFORMIN | 1,697 | 1.9% | 277 | 796 | 246 |
| RISPERIDONE | 1,651 | 2.1% | 127 | 967 | 158 |
| OLANZAPINE | 1,644 | 3.2% | 210 | 797 | 226 |
| TRAMADOL | 1,630 | 2.2% | 274 | 763 | 243 |
| AMIODARONE | 1,589 | 6.3% | 156 | 992 | 240 |
| LAMOTRIGINE | 1,569 | 3.3% | 98 | 683 | 136 |