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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Cytochrome P450 2C8 Inhibitors [MoA]: Side Effects & Safety Data for 21 Drugs

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Cytochrome P450 2C8 Inhibitors [MoA] includes 21 drugs with a combined 185,338 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.

21
Drugs in Class
185,338
Combined Reports

All Cytochrome P450 2C8 Inhibitors [MoA] Drugs Ranked by Reports

Drug Brand Name Reports Deaths Hosp. Death Rate
CLOPIDOGREL BISULFATE Clopidogrel 46,012 5,327 24,774 11.6%
ABIRATERONE Abiraterone Acetate 34,511 7,180 8,816 20.8%
NILOTINIB nilotinib 23,171 4,543 4,846 19.6%
PAZOPANIB Pazopanib 21,208 5,612 4,347 26.5%
CANNABIDIOL Epidiolex 18,243 1,563 5,149 8.6%
DEFERASIROX Deferasirox 11,322 2,661 4,008 23.5%
TUCATINIB TUKYSA 6,042 640 1,717 10.6%
ATAZANAVIR Atazanavir Sulfate 5,434 425 1,112 7.8%
PERAMPANEL Fycompa 4,446 249 1,760 5.6%
RIPRETINIB QINLOCK 4,432 465 948 10.5%
TRIMETHOPRIM Trimethoprim 3,191 211 1,264 6.6%
NICARDIPINE NICARDIPINE HYDROCHLORIDE 2,317 182 1,073 7.9%
LETERMOVIR PREVYMIS 1,416 252 398 17.8%
SELPERCATINIB RETEVMO 1,084 160 342 14.8%
RESMETIROM REZDIFFRA 881 26 50 3.0%
CLOPIDOGREL CLOPIDOGREL 644 95 300 14.8%
PIRTOBRUTINIB JAYPIRCA 437 130 144 29.7%
LEVOKETOCONAZOLE Recorlev 309 8 99 2.6%
TECOVIRIMAT TPOXX 137 27 43 19.7%
LONAFARNIB Zokinvy 59 6 14 10.2%
TRICLABENDAZOLE EGATEN 42 0 4 N/A

Common Side Effects in Cytochrome P450 2C8 Inhibitors [MoA] Drugs

Side EffectReportsDeaths
Death 16,645 16,547
Diarrhoea 10,570 877
Fatigue 10,294 749
Drug ineffective 8,536 740
Nausea 8,008 722
Seizure 6,274 170
Off label use 6,133 692
Gastrointestinal haemorrhage 5,926 1,011
Vomiting 5,600 657
Dyspnoea 5,268 937
View detailed side effects for this class → Compare drugs in this class →